Prof. Dr. Joachim Wiskemann
Dr. Rea Kühl and Maximilian Köppel
PEXO: Personalized Exercise Oncology – Study
The primary goal of the PEXO-Study is to identify groups of patients who are similar in regards to their health status, symptoms, attitudes towards physical activity and physical activity related health competence. Based on these groups, individualized training protocols as well as educational strategies will be developed that should increase the efficacy of exercise therapy and increase the likelihood of patients to engage in physical activity and a physically active lifestyle.
There is a large body of evidence supporting the beneficial impact of physical activity and exercise therapy in cancer patients. However, exercise programs that are individually tailored to the needs of the patients are scarce.
The PEXO study is a survey, e.g. patient are asked once to fill out a questionnaire (Cross sectional study). Overall 500 patients should be enrolled in the survey.
The PEXO study was already conducted on a cohort of 402 cancer patients at the Penn State Cancer Institute in Hershey Pennsylvania USA.
Sub-Study PEXO-M (especially for patients with multiple myeloma)
In cooperation with the Myeloma Center Heidelberg (Prof. Dr. Goldschmidt) the PEXO-M study is conducted. PEXO-M is a sub study of the PEXO study that exclusively enrolls patients with multiple myeloma.
Inclusion and exclusion criteria
- Adults with confirmed oncological diagnosis
- During therapy (chemotherapy, radiation therapy, immune therapy, anti-hormone therapy)
- German as native language or advanced German language skills
- Contraindication for physical training (e.g. severe heart disease, unstable bone metastases)
- ECOG Status ≥ 2 (impaired autonomy)
Start of recruitment June 2020