The research spectrum of the Medical Oncology Department has the aim to translate state-of-the-art basic research into clinical application as fast as possible. In line with the transfer function of translational research, we are working to offer patients new and more innovative tumor therapies in the future. The research groups in the Medical Oncology Department therefore have a common goal: Based on identifying new, molecular target structures and tumor-specific immunological mechanisms involved in carcinogenesis, they are aiming to develop therapies for prevention and delay of disease progression.
The research activities of the Medical Oncology Department aim to
- generate novel antibody-based immunotherapeutics (Prof. Dr. Krauss),
- systematically characterize tumor-host immune interactions and identify strategies for modulating such interactions towards effective anti-tumor responses (Prof. Dr. Jäger/PD Dr. Halama/Dr. Zörnig),
- identify tumor-specific anti-apoptotic mechanisms and to develop strategies to sensitize malignant cells towards treatment (Dr. Köhler),
- Clinical Cooperation Unit Applied Tumor-Immunity (CCU Prof. Dr. Jäger)
- develop analyses of the tumor microenvironment (Prof. Dr. Grabe)
- develop approaches and strategies for the combination of immunotherapy and virotherapy (CCU Prof. Dr. Dr. Ungerechts)
- NCT-EPOC: Ethics and Patient oriented Care in Oncology (Prof. Dr. Dr. Winkler)
- The Exercise Oncology (PD Dr. Wiskemann) Group investigates the effects of movement and sports intervention on side-effect profiles such as fatigue, physical weakness, polyneuropathy or urinary incontinence. In addition, they are engaged in basic research in order to better understand effect mechanisms.