Clinical Trials

Head- and Neck Tumors

Recruitment stopped
Ongoing Recruitment

BMS CA209-651

(first-line)
Title:An Open Label, Randomized, Two Arm Phase III Study of Nivolumab in Combination With Ipilimumab Versus Extreme Study Regimen (Cetuximab + Cisplatin/Carboplatin + Fluorouracil) as First Line Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Indication:Carcinoma, Squamous CellHead and Neck Neoplasms
Type of study:Phase III
Contact: Sarah Williams (Kontaktperson)
[sarah.williams2@med.uni-heidelberg.de]
Investigator: Dr. med. Jutta Sylvina Schreiber (Prüfer)
Trial Register: Die Studie ist bei den "U.S. National Institutes of Health" (ClinicalTrials.gov) registriert. Siehe NCT02741570
EudraCT: 2016-000725-39 (siehe EU klinisches Studienregister)

MEDI4736 (Eagle) D4193C00002

(second-line)
Title:A Phase III Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 Monotherapy and MEDI4736 in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Indication:Carcinoma, Squamous CellHead and Neck Neoplasms
Type of study:Phase III
Contact: Anette Manka-Stuhlik (Kontaktperson)
[anette.manka-stuhlik@med.uni-heidelberg.de]
Investigator: PD Dr. med. Jürgen Krauss (Prüfer)
Trial Register: Die Studie ist bei den "U.S. National Institutes of Health" (ClinicalTrials.gov) registriert. Siehe NCT02369874
EudraCT: 2014-003863-40 (siehe EU klinisches Studienregister)

LINGUA

(epidemiologisch)
Title:Identifikation von Kompensationsmechanismen zum Erhalt von Sprechen und Schlucken nach kombiniert ablativ/rekonstruktiven Operationen in der Mund-, Kiefer- und Gesichtschirurgie
Indication:Larynx
Type of study:Phase N/A
Contact: Regina Männl (Study Nurse)
[Regina.Maennl@med.uni-heidelberg.de]
Investigator: Dr. Dr. Katinka Kansy (Prüfer)
Trial Register: No trial registry number given.
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.

PROCURE

(epidemiologisch)
Title:Prospective evaluation of disease free survival and Quality of Life following microvascular reconstruction in early oral squamous cell carcinoma
Indication:Stoma Pharynx (C00, C01, C02, C03, C04, C05, C06, C07, C08, C09, C10, C11, C12, C13, C14)
Type of study:Phase N/A
Contact: Regina Männl (Study Nurse)
[Regina.Maennl@med.uni-heidelberg.de]
Investigator: Dr. Julius Moratin (Prüfer)
Trial Register: Die Studie ist beim "DRKS - Deutsches Register Klinischer Studien" registriert. Siehe DRKS00013041
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.

PROSS

(epidemiologisch, chirurgisch)
Title:Prospektive Untersuchungen zur rettungschirurgischen Therapie (Salvage Surgery) des Mundhöhlenkarzinoms (PROSS)
Indication:Mundhöhlenkarzinom
Type of study:Phase N/A
Contact: Regina Männl (Study Nurse)
[Regina.Maennl@med.uni-heidelberg.de]
Investigator: Dr. med. Dr. med. dent. Jens Bodem (Prüfer)
Trial Register: Die Studie ist beim "DRKS - Deutsches Register Klinischer Studien" registriert. Siehe DRKS00009255
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.

Sono-Studie

(radiologisch, supportive care trial)
Title:Einfluss einer Strahlentherapie auf die extrakraniellen Halsgefäße bei Patienten mit Kopf-Hals-Tumoren
Indication:Kopf-Hals-Tumoren
Type of study:Phase N/A
Contact: Ines Ludwig (Kontaktperson)
[Ines.Ludwig@med.uni-heidelberg.de]
Investigator: Prof. Dr. med. Oliver Müller (Prüfer)
Trial Register: No trial registry number given.
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.

CV-8102-008

Title:Phase I Study of Intratumoral CV8102 in Patients With Advanced Melanoma, Squamous Cell Carcinoma of the Skin, Squamous Cell Carcinoma of the Head and Neck, or Adenoid Cystic Carcinoma
Indication:Carcinoma, Melanoma, Carcinoma, Squamous Cell, Skin Neoplasms, Head and Neck Neoplasms, Carcinoma, Adenoid Cystic
Type of study:Phase I
Contact: Anette Manka-Stuhlik (Study Nurse)
[anette.manka-stuhlik@med.uni-heidelberg.de]
Trial Register: Die Studie ist bei den "U.S. National Institutes of Health" (ClinicalTrials.gov) registriert. Siehe NCT03291002
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.

S-229/216

Title:hypothesengenerierende Pilotstudie
Indication:-
Type of study:Phase N/A
Contact: Dr. med. Henrik Hauswald (Kontaktperson)
[henrik.hauswald@med.uni-heidelberg.de]
Investigator: Dr. med. Henrik Hauswald (Prüfer)
Trial Register: No trial registry number given.
EudraCT: Not stated. Non-interventional studies and studies not controlled by the Medicines Act do not have a EudraCT number.