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Acute lymphoblastic leukemia

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Acute lymphoblastic leukemia

Recruiting after consultation
Open recruiting

First line therapy

Title: A Multicentre, Randomized Trial in Adults With de Novo Philadelphia-Chromosome Positive Acute Lymphoblastic Leukemia to Assess the Efficacy of Ponatinib Versus Imatinib in Combination With Low-intensity Chemotherapy, to Compare End of Therapy With Indication for SCT Versus TKI, Blinatumomab and Chemotherapy in Optimal Responders and to Evaluate Blinatumomab in Suboptimal Responders (GMALL-EVOLVE)
Phase: II
Contact: Antje Heine / Kontaktperson
Email-Address: Antje.Heine(at)med.uni-heidelberg.de
Clinical Investigator: PD Dr. med. Simon Raffel
Registration: Die Studie ist bei den U.S. National Institutes of Health(ClinicalTrials.gov) registriert. Siehe NCT06061094
EU CTIS/EudraCT: Keine Registernummer angegeben. N/A:

Follow-up therapy

Title: Treatment of patients with relapsed or refractory CD19+ lym-phoid disease with T lymphocytes transduced by RV-SFG.CD19.CD28.4-1BBzeta retroviral vector – A unicenter Phase I/II clinical trial
Phase: I/II
Contact: Max Wingbermühle / Study Nurse
Email-Address: Max.Wingbermuehle(at)med.uni-heidelberg.de
Clinical Investigator: Prof. Dr. med. Michael Schmitt
Registration: Die Studie ist bei den U.S. National Institutes of Health(ClinicalTrials.gov) registriert. Siehe NCT03676504
EU CTIS/EudraCT: Siehe EU klinisches Studienregister EudraCT: 2016-004808-60

Title: A Modular Phase I/II, Open-label, Multi-Centre Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants with Advanced Haematologic Malignancies with KMT2Ar, NPM1m, or Other Genotypes Associated with HOX Overexpression
Phase: I/II
Contact: Melanie Bauer / Kontaktperson
Email-Address: Melanie.Bauer3(at)med.uni-heidelberg.de
Clinical Investigator: Dr. med. Tim Sauer
Registration: Die Studie ist bei den U.S. National Institutes of Health(ClinicalTrials.gov) registriert. Siehe NCT07155226
EU CTIS/EudraCT: Die Studie ist im EU-CTIS registriert. CTIS: 2025-521299-76-00

Surgical Study

There are currently no studies available

Radiotherapy Study

There are currently no studies available

Other study

Title: GMALL-Register und Biomaterialbank Biomaterialsammlung und prospektive Datenerfassung zu Diagnostik, Behandlung und Krankheitsverlauf der ALL des Erwachsenen
Phase: N/A
Contact: Antje Heine / Study Nurse
Email-Address: Antje.Heine(at)med.uni-heidelberg.de
Clinical Investigator: PD Dr. med. Simon Raffel
Registration: Keine Registernummer angegeben.
EU CTIS/EudraCT: Keine Registernummer angegeben. N/A:

Title: Zentrale Registrierung von Patientendaten und Biomaterialbank bei Aplastischen Anämien und Bone Marrow Failure Syndromen AA-BMF-Register
Phase: N/A
Contact: Martina Gronkowski / Kontaktperson
Email-Address: Martina.Gronkowski(at)med.uni-heidelberg.de
Clinical Investigator: Prof. Dr. med. Thomas Luft
Registration: Keine Registernummer angegeben.
EU CTIS/EudraCT: Keine Registernummer angegeben. N/A: