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SPECTRE makes movie buffs think of the 2015 James Bond film - but at the NCT Heidelberg, it's actually a study name. SPECTRE aims to use CAR-T cell therapy to treat solid tumors for the first time. The abbreviation CAR stands for chimeric antigen receptor; the cell therapy is based on the genetic modification of T cells in order to recognize specific antigens on the surface of tumour cells and destroy them in a targeted manner.

In recent years, CAR-T cell therapy has achieved remarkable success as an innovative approach to immunotherapy for blood cancers. SPECTRE would like to build on this and extend the method to other types of cancer; the focus is on breast cancer, but the approach could also open up new perspectives beyond this. You can read the full text (in German) here.

The article is taken from the current issue of our magazine Connect, which is dedicated to the 20th anniversary of NCT Heidelberg under the title 20plusZukunft. Every two weeks, we present a Connect highlight from the magazine.

The magazine is available to take away at many locations in the NCT Heidelberg building. Please help yourself and grab your own copy!

Would you like to read the entire Connect magazine? You can order it free of charge here or download it as a PDF file.